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It reduced IL types 4, 6, and 8 and tumor necrosis factor (TNF) alpha

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Key Takeaways From Human Trials Sublingual glutathione may lower LDL and total cholesterol in some people Full-group improvements in blood vessel function were not confirmed A small subgroup with poor baseline vessel health saw reduced arterial stiffness Sample sizes remain too small for strong clinical guidance Larger, longer studies are needed before making treatment claims Laboratory Research on Glutathione and Blood Vessel Cells A 2025 laboratory study looked at how glutathione affects human endothelial cells grown in a lab